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How cannabis gets you high and alters your perception

20 April is weed's unofficial holiday. In honour of the special day, we collected our answers to all your cannabis questions. This is the science of 420

By Grace Wade

20 April 2024

Our Science of cannabis series investigates some of the biggest questions about the drug

MR.Yanukit/Shutterstock

More than half a century ago, as legend has it, a group of five high school students in San Rafael, California, began meeting after class at 4.20pm to smoke cannabis. One of them later went on to work with the Grateful Dead, sharing their story and ultimately popularising the number’s association with marijuana. Now, 20 April is recognised worldwide as weed’s unofficial holiday.

Whether you plan on celebrating today or are simply curious about how cannabis affects the body and mind, here are seven highlights from our Science of cannabis series. These stories explore cannabis’s history, how it gets us high and what the science really says about its medical potential (spoiler: it doesn’t treat anxiety).

How does cannabis get us high?

Why does weed give you the ‘munchies’?

Is it better to vape, smoke or take edibles?

How high is too high to drive?

Can cannabis help you sleep?

Does cannabis make you more creative?

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The science of cannabis

As the use of marijuana and its compounds rises around the world, New Scientist explores the latest research on the medical potential of cannabis, how it is grown and its environmental impact, the way cannabis affects our bodies and minds and what the marijuana of the future will look like.

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